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| 缓释片中新斯的明的含量测定 | |
| 引用本文： | 罗文,谭群友,熊华蓉,赵春景,张景勍.缓释片中新斯的明的含量测定[J].光谱实验室,2011,28(5):2623-2625. |
| 作者姓名： | 罗文 谭群友 熊华蓉 赵春景 张景勍 |
| 作者单位： | 1. 重庆医科大学药物高校工程研究中心和生物化学与分子药理学重点实验室 重庆市渝中区医学院路1号400016 2. 第三军医大学大坪医院野战外科研究所胸外科 重庆市渝中区大坪长江支路10号400042 3. 重庆医科大学附属第二医院药剂科 重庆市临江路76号400010 |
| 基金项目： | 教育部博士点基金资助项目(20095503120008); 重庆市教育委员会资助项目(首批高等学校优秀人才资助,KJ090308) |
| 摘 要： | 采用紫外分光光度法测定新斯的明缓释片中新斯的明的含量及对其稳定性进行研究。结果表明,新斯的明浓度在80—560μg.mL-1范围内与吸光度呈良好的线性关系,回归方程为：A=0.0016C-0.0089,r=0.9999;平均回收率为100.46%,RSD为0.89%（n=9）。该法简便、快速,重现性好,结果准确可靠。 |
| 关 键 词： | 新斯的明 缓释片 紫外分光光度法 |
Determination of Neostigmine in Sustained-Release Tablets |
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| LUO Wen,TAN Qun-You,XIONG Hua-Rong,ZHAO Chun-Jing,ZHANG Jing-Qing.Determination of Neostigmine in Sustained-Release Tablets[J].Chinese Journal of Spectroscopy Laboratory,2011,28(5):2623-2625. | |
| Authors: | LUO Wen TAN Qun-You XIONG Hua-Rong ZHAO Chun-Jing ZHANG Jing-Qing |
| Institution: | LUO Wen TAN Qun-Youa XIONG Hua-Rong ZHAO Chun-Jingb ZHANG Jing-Qing(Medicine Engineering Research Center,Chongqing Key Laboratory of Biochemical & Molecular Pharmacology,Chongqing Medical University,Chongqing 400016,P.R.China)a(Daping Hospital & Research Institute of Surgery,Third Military Medical University,Chongqing 400042,P.R.China)b(Second Affiliated Hospital,Chongqing 400010,P.R.China) |
| Abstract: | Neostigmine sustained-release tablets were determined by UV spectrophotometry,and its stability was studied.The neostigmine had a good liner relationship range from 80μg·mL-1 to 560μg·mL-1.The regression equation was A=0.0016C-0.0089,r=0.9999.The average recovery rate was 100.46%,RSD=0.89%（n=9）.The method is simple,rapid and accurate,and has good repeatability. |
| Keywords: | Neostigmine Sustained-Release Tablets UV Spectrophotometry |
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