Convenient method of synthesizing 3-ethoxycarbonyl indoles |
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| Authors: | Islam M Shahidul Brennan Courtney Wang Qinwei Hossain M Mahmun |
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| Institution: | Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, USA. |
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| Abstract: | We have developed a convenient two-step procedure for the synthesis of 3-ethoxycarbonyl indoles from commercially available materials. The two-step procedure involves the synthesis of 2-aryl-3-hydroxypropenoic acid ester, followed by a catalytic reduction. This method is efficient, simple, and selective. |
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