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Metabolism of Pyrene and Chrysene in Epithelial Human Bronchial and Hamster Lung Cells |
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| Authors: | J Jacob G Grimmer G Raab M Emura M Riebe U Mohr |
| Institution: | 1. Biochemical Institute for Environmental Carcinogens , Lurup 4, D-2070, Groβhansdorf, FRG;2. Institute for Experimental Pathology, Medical School , D-3000, Hannover 61, FRG |
| Abstract: | Abstract The metabolism of pyrene and chrysene in epithelial human bronchial and in hamster lung cells has been studied and found to be very similar in both systems, although it differs from that observed in rat lung microsomes. Metabolite profiles have been analyzed by means of capillary GC and by GC/MS. |
| Keywords: | Metabolism of pyrene metabolism of chrysene human lung cell cultures hamster lung cell cultures PAHs |