Determination of nine emerging pesticides at trace level in aqueous samples using fully automated on-line solid phase extraction coupled with liquid chromatography-mass spectrometry |
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| Authors: | Qian Sun Min Zhang Zuliang Chen Chenkai Gu |
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| Institution: | 1. State Key Laboratory of Marine environmental Science , Environmental Science Research Centre, Xiamen University , Xiamen 361005 , China;2. Key Laboratory of Urban Environment and Health , Institute of Urban Environment, Chinese Academy of Sciences , Xiamen 361021 , China;3. State Key Laboratory of Marine environmental Science , Environmental Science Research Centre, Xiamen University , Xiamen 361005 , China;4. School of Chemistry and Materials Science, Fujian Normal University , Fuzhou 350007 , China |
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| Abstract: | On-line solid phase extraction (SPE) coupled to liquid chromatography-mass spectrometry (LC-MS) offers an easy and fast strategy to analyze the organic contaminants in environmental samples with high sensitivity and selectivity. This paper described an in-house designed on-line SPE system and an on-line SPE-LC-MS method for the determination of pesticides at trace levels in water samples. The system was assembled from an eight-position valve, a piston pump, a six-port valve and a C18 SPE column, and significantly reduced analysis time by achieving full automation. Moreover, the use of a large enrichment volume (50?mL) significantly enhanced method sensitivity. Using this on-line SPE system, an on-line SPE-LC-MS method was developed for the determination of nine pesticides at trace levels in lake water and seawater sample. Under optimized conditions, method detection limits (MDLs) were 1.00–10.0?ng?L?1. |
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| Keywords: | on-line SPE LC-MS pesticides water samples |
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