Toxaphene (Polychlorinated Camphenes) Analysis in Human Blood |
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| Authors: | U. S. Gill H. M. Schwartz B. Wheatley |
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| Affiliation: | 1. Trace Contaminants Section, Occupational and Environmental Health Services Tunney's Pasture , Bldg # 17, Ottawa, Ontario, K1A OL3, Canada;2. Research and Development/Environmental Contaminants, Medical Services Branch, Health Canada Tunney's Pasture , Ottawa, Ontario, K1A OL3, Canada |
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| Abstract: | Abstract A method for the determination of toxaphene in whole blood using gas chromatography (GC)-electron capture negative ion ECNI/MS and pure polychlorobornane congerners has been evaluated. Blood samples were extracted with hexane/acetone (9:1), extracts defatted with sulfuric acid, analytes fractionated on Carbopack-C/ Florisil (or silica gel) SPE columns then concentrated to final volumes for GC-ECNI/MS analysis. For confirmation, interference from PCBs and other organochlorine pesticides were removed by nitration. |
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| Keywords: | Blood Toxaphene ECNI/MS |
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