Facile synthesis of salmochelin S1, S2, MGE, DGE, and TGE |
| |
| Authors: | Xiaolong Yu Yijing Dai Tao YangMichel R Gagné Hegui Gong |
| |
| Institution: | a Shanghai University, Department of Chemistry, Shanghai 200444, Chinab University of North Carolina at Chapel Hill, Department of Chemistry, Chapel Hill, NC 27599, USA |
| |
| Abstract: | Salmochelin S1, S2, MGE, DGE, and TGE were prepared through amide bond connection of an aryl C-glucosyl acyl chloride (Ar1COCl) and serine ester amines, followed by hydrogenolysis of the per-benzylated precursors. Each synthesis employed a highly diastereoselective Ni-catalyzed Negishi approach to the aryl C-glycoside subunit. |
| |
| Keywords: | Salmochelin Total synthesis Aryl β-C-glucoside |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
