Formation of polyelectrolyte multilayer architectures with embedded DMPC studied in situ by neutron reflectometry |
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Authors: | Delajon Christophe Gutberlet Thomas Steitz Roland Möhwald Helmuth Krastev Rumen |
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Institution: | Max-Planck Institute of Colloids and Interfaces, Wissenschaftspark Golm, 14424 Potsdam, Germany. |
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Abstract: | The coupling of lipid molecules to polymer components in a planar biomimetic model membrane made of a lipid bilayer (dimyristoylphosphatidylcholine) supported by polyelectrolyte multilayers is studied. The polyelectrolyte support was prepared by layer-by-layer deposition of positively charged poly(allylamine hydrochloride) (PAH) and negatively charged poly(sodium 4-styrenesulfonate) (PSS). Two polymer sample terminations were considered: positively charged (PAH-terminated) and negatively charged (PSS-terminated). Neutron reflectometry studies showed that, whereas positively charged samples did not favor the deposition of lipid, negatively charged samples allowed the deposition of a lipid bilayer with a thickness of approximately 5 nm. In the latter case, formation of polyelectrolyte layers after the deposition of the lipid layer was also possible. |
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