Nanoparticle encapsulated silver carbene complexes and their antimicrobial and anticancer properties: a perspective |
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Authors: | Youngs Wiley J Knapp Amanda R Wagers Patrick O Tessier Claire A |
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Institution: | Center for Silver Therapeutics Research, Department of Chemistry, University of Akron, Akron, OH 44325, USA. youngs@uakron.edu |
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Abstract: | This perspective discusses the uses of silver for both antimicrobial and anticancer applications. It focuses on the synthesis of silver N-heterocyclic carbene complexes (SCCs) and their in vitro efficacy against a broad spectrum of bacteria, as well as their antitumor properties. Finally, different polymeric nanoparticles are discussed as delivery vehicles for the encapsulation of SCCs and other therapeutic agents for use in vivo. |
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