Total synthesis of bistramide A |
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| Authors: | Lowe Jason T Wrona Iwona E Panek James S |
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| Institution: | Department of Chemistry and Center for Chemical Methodology and Library Development, Metcalf Center for Science and Engineering, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA. |
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| Abstract: | An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product. structure: see text]. |
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