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Effects of the deletion of the <Emphasis Type="Italic">Escherichia coli</Emphasis> frataxin homologue CyaY on the respiratory NADH:ubiquinone oxidoreductase
Authors:Thomas Pohl  Julia Walter  Stefan Stolpe  Joel H Defeu Soufo  Peter L Grauman  Thorsten Friedrich
Institution:1.Institute of Organic Chemistry and Biochemistry,University of Freiburg,Freiburg,Germany;2.Institute of Microbiology,University of Freiburg,Freiburg,Germany
Abstract:

Background  

Frataxin is discussed as involved in the biogenesis of iron-sulfur clusters. Recently it was discovered that a frataxin homologue is a structural component of the respiratory NADH:ubiquinone oxidoreductase (complex I) in Thermus thermophilus. It was not clear whether frataxin is in general a component of complex I from bacteria. The Escherichia coli homologue of frataxin is coined CyaY.
Keywords:
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