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Antimicrobial silver nanoparticles generated on cellulose nanocrystals
Authors:Nicolas Drogat  Robert Granet  Vincent Sol  Abdelmajid Memmi  Naïma Saad  Carmen Klein Koerkamp  Philippe Bressollier  Pierre Krausz
Institution:1.Laboratoire de Chimie des Substances Naturelles,Université de Limoges,Limoges,France;2.Laboratoire d’Analyses, Traitement et Valorisation des Polluants de l’Environnement et des Produits, Faculté de Pharmacie,Université de Monastir,Monastir,Tunisie
Abstract:We describe a new approach to the formation of silver nanoparticles (Ag NPs) using cellulose nanocrystals. The process involves periodate oxidation of cellulose nanocrystals, generating aldehyde functions which, in turn, are used to reduce Ag+ into Ag0 in mild alkaline conditions. The nanoparticles were characterized using transmission electron microscopy (TEM) and ultraviolet–visible absorption spectroscopy. From the microscope studies (TEM) we observed that Ag NPs have spherical shape with a size distribution comprise between 20 and 45 nm. The antibacterial activity was assessed using the minimum inhibitory concentration. The antibacterial assays compare favourably with most of other experiments conducted with the same species.
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