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2-(Trimethylsilyl)ethanol as a new alcohol equivalent for copper-catalyzed coupling of aryl iodides |
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| Authors: | Mullick Dibakar Anjanappa Prakash Kumaravel Selvakumar Kandasamy Ruckmani Manickam Sivakumar |
| Institution: | a Synthetic Chemistry, Syngene International Ltd, Biocon Park, Plot 2 & 3, Jigani Link Road, Bommasandra Industial Area, Bangalore 560 099, India b Bharathidasan Institute of Technology, Bharathidasan University, Tiruchirappalli 620 024, India c Department of Pharmaceutical Technology, Anna University, Truichirappalli 620 024, India d Department of Chemical & Environmental Engineering, University of Nottingham (Malaysia campus), Semenyih 43500, Malaysia |
| Abstract: | 2-(Trimethylsilyl)ethanol as a new alcohol equivalent has been employed for copper-catalyzed coupling of aryl iodides. Using mild reaction conditions, it has been observed that substituted phenols and phenols with sensitive functional groups can be readily prepared. |
| Keywords: | Copper catalysis Alcohol surrogates Cross-coupling 2-(Trimethylsilyl)ethanol |
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