Facile synthesis of 3,3-di(heteroaryl)indolin-2-one derivatives catalyzed by ceric ammonium nitrate (CAN) under ultrasound irradiation |
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| Authors: | Shun-Yi Wang |
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| Institution: | The Key Lab. of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou (Soochow) University, Jiangsu 215123, China |
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| Abstract: | Ceric ammonium nitrate efficiently catalyzes the reaction of isatin with indoles under sonic waves to afford symmetrical 3,3-di(indolyl)indolin-2-ones in excellent yields, as well as the reaction of 3-hydroxy-3-indolylindolin-2-ones with indoles, pyrrole to afford the corresponding adducts in excellent yields, which provides an efficient route to the synthesis of symmetrical and unsymmetrical 3,3-di(indolyl)indolin-2-one derivatives, respectively. |
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| Keywords: | 3 3-Di(heteroaryl)indolin-2-one CAN Indole Isatin |
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