Total synthesis of FR901464: second generation |
| |
| Authors: | Hajime Motoyoshi |
| |
| Institution: | Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan |
| |
| Abstract: | FR901464, a potent cell cycle inhibitor, was synthesized in a convergent manner using natural chiral pool, l-threonine, ethyl (S)-lactate and 2-deoxy-d-glucose as starting materials. |
| |
| Keywords: | FR901464 Asymmetric synthesis Coupling reactions Cell cycle inhibitor |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
