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Callipeltins F-I: new antifungal peptides from the marine sponge Latrunculia sp. |
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| Authors: | Valentina Sepe Nicola Borbone Giuseppe Bifulco Anna Catania |
| Institution: | a Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli ‘Federico II’, via D. Montesano 49, 80131 Naples, Italy b Dipartimento di Scienze Farmaceutiche, Università di Salerno, via Ponte don Melillo, Fisciano (SA) 84084, Italy c Divisione di Medicina Interna, Ospedale Maggiore di Milano IRCCS, 20122 Milano, Italy |
| Abstract: | Four new antifungal peptides, callipeltins F-I, were isolated from the marine sponge Latrunculia sp., collected off Vanuatu islands. Their structures were elucidated by NMR and MS analysis. The new callipeltins exhibited anti Candida activity in the 10−4 M range. |
| Keywords: | Callipeltin Peptides Antifungal |
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