|
|||||
|
|
Synthesis of 2′-dealkylmumbaistatin |
|
| Authors: | Karsten Krohn Jan Diederichs Muhammad Riaz |
| Affiliation: | Department of Chemistry, University of Paderborn, Warburger Str. 100, D-33098 Paderborn, Germany |
| Abstract: | The sterically congested 1,2,3-substituted 3′-dealkyl mumbaistatin derivatives 16, 20, and 21 were prepared for the first time by base-catalyzed cyclization of the 2,3-bis-substituted naphthoquinone precursor 11 followed by bromine mediated photooxidation and methyl ether cleavage. |
| Keywords: | 3&prime -Dealkyl mumbaistatin Anthraquinone synthesis Base-catalyzed aldol cyclization Photooxidation |
| 本文献已被 ScienceDirect 等数据库收录！ | |