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Observation of Brownian relaxation of magnetic nanoparticles using HTS SQUID |
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| Authors: | O V Snigirev I I Soloviev A S Kalabukhov M L Chukharkin |
| Institution: | 1.Department of Semiconductor Physics, Faculty of Physics,Moscow State University,Moscow,Russia;2.Skobeltsyn Institute of Nuclear Physics,Moscow State University,Moscow,Russia;3.Chalmers University of Technology,Gothenburg,Sweden |
| Abstract: | We analyzed the sensitivity of a separationless immunoassay scheme using functionalized magnetic nanoparticles (MNPs) and a sensitive HTS SQUID magnetometer. The signal of a 100 μL sample at a concentration of 1 mg/mL and field of 7.5 nT was 20 mΦ0. This makes it possible for the sensitivity to be within the range of 50 ng/mL at the required time of up to 100 s per a point in the frequency spectrum. |
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