Bidentate carbenoid ester coordination in ruthenium(II) Schiff-base complexes leading to excellent levels of diastereo- and enantioselectivity in catalytic alkene cyclopropanation |
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Authors: | Munslow I J Gillespie K M Deeth R J Scott P |
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Institution: | Department of Chemistry, University of Warwick, Coventry, UK CV4 7AL. |
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Abstract: | Exceptionally high stereoselectivity (ee < or = 98%, dr < or = 99:1) in the cyclopropanation of alkenes with ethyl diazoacetate using a non-planar ruthenium(II) Schiff-base precatalyst is a result of eta 2C,O binding of the carbenoid ester intermediate, according to DFT calculations. |
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