Enzymetically Regulating the Self‐Healing of Protein Hydrogels with High Healing Efficiency |
| |
Authors: | Dr. Yuzhou Gao Prof. Quan Luo Shanpeng Qiao Liang Wang Prof. Zeyuan Dong Jiayun Xu Prof. Junqiu Liu |
| |
Affiliation: | State Key laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Road, Changchun 130012 (China) |
| |
Abstract: | Enzyme‐mediated self‐healing of dynamic covalent bond‐driven protein hydrogels was realized by the synergy of two enzymes, glucose oxidase (GOX) and catalase (CAT). The reversible covalent attachment of glutaraldehyde to lysine residues of GOX, CAT, and bovine serum albumin (BSA) led to the formation and functionalization of the self‐healing protein hydrogel system. The enzyme‐mediated protein hydrogels exhibit excellent self‐healing properties with 100 % recovery. The self‐healing process was reversible and effective with an external glucose stimulus at room temperature. |
| |
Keywords: | dynamic covalent bonds enzyme mediation glucose oxidase protein hydrogels self‐healing |
|