Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy |
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Authors: | Li Shuwei Marthandan Nishanth Bowerman Dawn Garner Harold R Kodadek Thomas |
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Affiliation: | Department of Internal Medicine, Center for Biomedical Inventions, University of Texas Southwestern Medical Center, Dallas, TX 75390-8573, USA. |
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Abstract: | We report here a strategy for the photolithographic synthesis of diverse, spatially addressable arrays of cyclic peptides which employs a differential deprotection strategy for the combinatorial addition of side chains to a pre-fabricated cyclic core. |
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