Diarrhetic shellfish toxins |
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Authors: | T Yasumoto M Murata Y Oshima M Sano GK Matsumoto J Clardy |
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Institution: | Faculty of Agriculture, Tohoku University, Tsutsumidori, Amemiya, Sendai 980 Japan;Department of Chemistry, Baker Laboratory, Cornell University, Ithaca, NY 14853 U.S.A. |
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Abstract: | As the causative agents of a new type of shellfish poisoning, named diarrhetic shellfish poisoning, okadaic acid, 35(S)-methylokadaic acid, 7-O-acyl derivatives of 35(S)-methylokadaic acid, two novel polyether lactones named pectenotoxin-1 and -2 have been isolated and had their structures determined. Three pectenotoxin analogues were also present. In addition to the previously identified Dinophysis fortii, D. acuminata was newly suggested as a source of toxins. |
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