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Diarrhetic shellfish toxins
Authors:T Yasumoto  M Murata  Y Oshima  M Sano  GK Matsumoto  J Clardy
Institution:Faculty of Agriculture, Tohoku University, Tsutsumidori, Amemiya, Sendai 980 Japan;Department of Chemistry, Baker Laboratory, Cornell University, Ithaca, NY 14853 U.S.A.
Abstract:As the causative agents of a new type of shellfish poisoning, named diarrhetic shellfish poisoning, okadaic acid, 35(S)-methylokadaic acid, 7-O-acyl derivatives of 35(S)-methylokadaic acid, two novel polyether lactones named pectenotoxin-1 and -2 have been isolated and had their structures determined. Three pectenotoxin analogues were also present. In addition to the previously identified Dinophysis fortii, D. acuminata was newly suggested as a source of toxins.
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