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Synthesis of mevalonolactone (hiochic acid lactone) employing asymmetric epoxidation as the key-step |
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| Authors: | Kenji Mori Katsuhide Okada |
| Affiliation: | Department of Agricultural Chemistry, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113 Japan |
| Abstract: | (R)( — )-Mevalonolactone (hiochic acid lactone)of 91–93%e.e. was synthesized from an achiral starting material employing the Sharpless asymmetric epoxidation as the key-step. |
| Keywords: | Present address : Laboratory of Food Science Faculty of Education amagata University Yamagata 990 Japan. |
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