A facile route to vinyl- and arylphosphonates by vinyl and aryl radical trapping with (MeO)3P |
| |
Authors: | Jiao Xian-Yun Bentrude Wesley G |
| |
Affiliation: | Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA. |
| |
Abstract: | The generation of vinyl or aryl radicals under classical, thermal AIBN/n-Bu(3)SnH conditions at 80 degrees C in the presence of an excess of (MeO)(3)P gives rise to the corresponding vinyl- or arylphosphonates in good yields. This approach complements the photochemical reactions of the same systems previously used. Reactions with the individual stereoisomers of MeCH=CHMeBr (thermal AIBN/n-Bu(3)SnH conditions) afford a radical-equilibrated 96/4 E/Z ratio of vinylphosphonates. Substitution of (TMS)(3)SiH for n-Bu(3)SnH yields an approximately 1/1 ratio of separable E and Z vinylphosphonate diastereomers. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|