2型糖尿病患者血清钙镁与甲状腺激素含量变化及临床意义

为了监测 2型糖尿病人血清钙、镁和甲状腺激素含量 ,分析其临床意义及相关性 ,应用放射免疫分析法测定了 1 1 5例 2型糖尿病及 1 5 0例健康人血清甲状腺激素含量。同时用美国杜邦RXL自动生化仪测定了其血清钙、镁含量。结果表明 ,在 2型糖尿病伴有明显并发症者血镁、FT3水平明显降低 (P <0 0 5 ) ,钙镁两种元素与甲状腺激素水平无明显相关性。 2型糖尿病患者适当补镁对预防其并发症是有益的 ,测定FT3 等可作为判断 2型糖尿病严重程度和估计预后的参考指标。

The Changes and Clinical Significance of the Concentration of Serum Calcium,Magnesium and Thyroid Hormone in Type 2 Diabetes Mellitus Patients

To analyse the clinical signaficance and correlation of the concentration of serum calcium,magnesium and thyroid hormone in type 2 diabetes mellitus patients,the concentrations of serum thyroid hormone in 115 type 2 diabetes mellitus patients and 150 healthy persons were determined by radioimmunoanalysis.Meanwhile,their serum calcium and magnesium were determined by Dimension RXL clinical chemistry system made in USA. The results show that in the type 2 diabetes mellitus patients with obvious complications,their concentration of serum magnesium and FT 3 declines significantly( P <0 05).There is no significant correlation between the two elements:calcium,magnesium and thyroid hormone.It is useful to prevent the complications by supplying magnesium to type 2 diabetes mellitus patients.The concentration of serum FT 3 is the conference index to diagnose the serionsness and evaluate the prognosis of type 2 diabetes mellitus.