Molecular angiogenesis. |
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| Authors: | M Klagsbrun M A Moses |
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| Institution: | Department of Surgery, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. klagsbrun@a1.tch.harvard.edu. |
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| Abstract: | New insights into the mechanisms by which blood vessels develop (angiogenesis) have been gained recently, primarily by the identification of factors that inhibit and promote this process. Angiogenesis-stimulating factors are being used to promote growth of new blood vessels in ischemic disease. In contrast, anti-angiogenesis factors are being used as inhibitors of neovascularization to control tumor growth and metastasis. |
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