Leufolins A and B, potent butyrylcholinesterase-inhibiting flavonoid glucosides from Leucas urticifolia |
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| Authors: | Atia-tun-Noor Fatima Itrat Ahmad Ijaz Malik Abdul Afza Nighat Iqbal Lubna Latif Mehreen Khan Sher Bahadar |
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| Institution: | International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. |
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| Abstract: | New flavonoidal glucosides leufolins A (1) and B (2), have been isolated from the ethyl acetate soluble fraction of the whole plants of Leucas urticifolia. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Both of these compounds exhibited significant inhibitory potential against the enzyme butyrylcholinesterase. |
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