| DNA与纳米结构的相互作用及基于力电作用的测序技术 |
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| 引用本文： | 李振海,杨卫. DNA与纳米结构的相互作用及基于力电作用的测序技术[J]. 力学进展, 2011, 41(6): 722-729. DOI: 10.6052/1000-0992-2011-6-lxjzJ2010-094 |
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| 作者姓名： | 李振海 杨卫 |
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| 作者单位： | 1.清华大学航天航空学院 |
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| 摘 要： | 本文概述基于力电作用的两类DNA测序技术. 这两类测序技术分别依赖DNA与纳米孔或DNA与碳纳米管间的相互作用来实现. 文中依次介绍以上两种纳米结构的测序方法, 包括: 相应纳米结构的制备、与DNA相互作用的表征、测序原理、及各自的研究现状.
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| 关 键 词： | 纳米孔，碳纳米管，DNA测序 |
| 收稿时间： | 2010-08-30 |
| 修稿时间： | 2011-04-18 |
DNA SEQUENCING METHOD BASED ON ELECTRO-MECHANICAL EFFECTS BETWEEN DNA AND NANO-STRUCTURES |
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| LI Zhenhai ,YANG Wei , AML. DNA SEQUENCING METHOD BASED ON ELECTRO-MECHANICAL EFFECTS BETWEEN DNA AND NANO-STRUCTURES[J]. Advances in Mechanics, 2011, 41(6): 722-729. DOI: 10.6052/1000-0992-2011-6-lxjzJ2010-094 |
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| Authors: | LI Zhenhai YANG Wei AML |
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| Affiliation: | LI Zhenhai 1,YANG Wei 2,1 AML,Department of Engineering Mechanics,Tsinghua University,Beijing 100084,China 2 University Office,Zhejiang University,Hangzhou 310058,China |
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| Abstract: | This review outlines two categories of recent developments in DNA sequencing methods that are based upon electro-mechanical effects.These two methods utilize the interactions between DNA and a nanopore,and between DNA and a carbon nanotube respectively.In this review,we describe the sequencing methods associated with these two nano-structures,including the structure fabrication,the interaction with DNA,the sequencing principle,and the research status. |
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| Keywords: | nanopore carbon nanotube DNA sequencing |
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