Synthesis and Antimicrobial Activity of a Pyridine Complex of (Acetato)[5,10,15,20-tetrakis(N-methylpyridin- 4-yl)porphinato]manganese(III) Tetratosylate |
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| Authors: | E. N. Ovchenkova N. G. Bichan A. V. Lyubimtsev E. V. Garasko T. N. Lomova |
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| Affiliation: | 1.G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences,Ivanovo,Russia;2.Ivanovo State University of Chemistry and Technology,Ivanovo,Russia;3.Ivanovo State Medical Academy,Ministry of Health of the Russian Federation,Ivanovo,Russia |
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| Abstract: | Aiming at preparation of new biologically active donor?acceptor complexes, a water-soluble manganese(III) complex with 5,10,15,20-tetrakis(N-methylpyridin-4-yl)porphine tetratosylate was synthesized and its reaction with pyridine was studied by spectrophotometry using the molar ratio method. In water a 1: 1 donor?acceptor complex with pyridine is formed. The chemical structure of the compounds was established by spectral methods. (Acetato)[5,10,15,20-tetrakis(N-methylpyridin-4-yl)porphinato]manganese(III) tetratosylate and especially its donor?acceptor complex with pyridine showed an antifungal activity against Candida albicans. |
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