Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts |
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| Authors: | D. A. Tatarinov N. V. Terekhova A. D. Voloshina A. S. Sapunova A. P. Lyubina V. F. Mironov |
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| Affiliation: | 1.Arbuzov Institute of Organic and Physical Chemistry,Kazan Scientific Center of the Russian Academy of Sciences,Kazan, Tatarstan,Russia;2.Kazan (Volga Region) Federal University,Kazan, Tatarstan,Russia |
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| Abstract: | New dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium salts bearing various substituents at the phosphorus atom were synthesized. Antimicrobial activity of the salts obtained was estimated. Derivatives with 2-methoxyphenyl substituents at the phosphorus atom are most active against grampositive bacteria. Herewith, dibenzyl-substituted phosphonium derivatives possess the best antifungal activity. |
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