首页 | 本学科首页   官方微博 | 高级检索  
     


Pummerer reaction intermediate as an initiating function for cationic olefin cyclization
Authors:Y. Tamura  H. Maeda  S. Akai  K. Ishiyama  H. Ishibashi
Affiliation:Faculty of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, Japan
Abstract:Treatment of N-(2-methyl-2-propenyl)-N-methyl-α-(methylsulfinyl)acetamide (6a) with trifluoroacetic anhydride caused the cationic olefin cyclization through a Pummerer reaction intermediate to give the six-membered lactams 7 and 8. Similar reaction converted N-2-butenyl-N-methyl-a-(methylsulfinyl)acetamide (6b) to the five-membered lactam 9, and N-2-propenyl-N-methyl-α-(methylsulfinyl)- acetamide (6c) to the five-membered lactams 11 and 12.
Keywords:
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号