Ultrasound effect on the aromatic nucleophilic substitution reactions on some haloarenes |
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Authors: | Meciarová Mária Toma Stefan Magdolen Peter |
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Affiliation: | Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-2, SK-842 15 Bratislava, Slovak Republic. mmeciarova@fns.uniba.sk |
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Abstract: | The sonochemical nucleophilic aromatic substitutions on haloarenes with different amines have been studied. A beneficial ultrasound effect was observed and high yields of the products were obtained after 15-30 min sonication. The reaction course of the nucleophilic aromatic substitution was found to be strongly dependent on nucleophilicity, bulkiness, and boiling point of amines as well as on the electron-withdrawing property of the substituents on the haloarenes. |
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