C−H Functionalisation for Hydrogen Isotope Exchange |
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| Authors: | Dr. Jens Atzrodt Dr. Volker Derdau Prof. Dr. William J. Kerr Dr. Marc Reid |
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| Affiliation: | 1. Isotope Chemistry and Metabolite Synthesis, Integrated Drug Discovery, Medicinal Chemistry, Frankfurt, Germany;2. Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, Glasgow, Scotland, UK |
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| Abstract: | The various applications of hydrogen isotopes (deuterium, D, and tritium, T) in the physical and life sciences demand a range of methods for their installation in an array of molecular architectures. In this Review, we describe recent advances in synthetic C?H functionalisation for hydrogen isotope exchange. |
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| Keywords: | catalysis C− H functionalization drug discovery hydrogen isotope exchange |
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