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A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates
Authors:Xiang Yun  Qian Xiaoqing  Chen Ying  Zhang Yuyong  Chai Yaqin  Yuan Ruo
Institution:Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yunatswu@swu.edu.cn
Abstract:Reagentless, sensitive and multiplexed analysis of gyrB and K-ras gene biomarkers is achieved based on the proximity changes of two different redox-tags to the electrode surface upon DNA hybridizations, and the presence of the two gene biomarkers also acts as inputs and activates the logic gate.
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