A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates |
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Authors: | Xiang Yun Qian Xiaoqing Chen Ying Zhang Yuyong Chai Yaqin Yuan Ruo |
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Institution: | Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yunatswu@swu.edu.cn |
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Abstract: | Reagentless, sensitive and multiplexed analysis of gyrB and K-ras gene biomarkers is achieved based on the proximity changes of two different redox-tags to the electrode surface upon DNA hybridizations, and the presence of the two gene biomarkers also acts as inputs and activates the logic gate. |
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