Benedict's solution/ vitamin C: An alternative catalytic protocol for the synthesis of regioselective‐1,4‐disubstituted‐1H‐1,2,3‐triazoles at room temperature |
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| Authors: | Manashjyoti Konwar Roktopol Hazarika Abdul A Ali Mitali Chetia Nageshwar D Khupse Prakash J Saikia Diganta Sarma |
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| Institution: | 1. Department of Chemistry, Dibrugarh University, Dibrugarh, Assam, India;2. Centre for Materials for Electronics Technology, Pune, India;3. Analytical Chemistry Division, CSIR‐North East Institute of Science & Technology, Jorhat, Assam, India |
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| Abstract: | A novel and highly efficient method for the synthesis of 1,4‐disubstituted‐1H‐1,2,3‐triazoles by copper‐catalyzed azide‐alkyne cycloaddition has been developed. This economic and sustainable protocol uses a readily available Benedict's solution/Vitamin C catalyst system affording a wide range of 1,4‐disubstituted‐1H‐1,2,3‐triazoles under mild conditions. |
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| Keywords: | 1 4‐disubstituted‐1H‐1 2 3‐triazole azide‐alkyne cycloaddition Benedict's solution vitamin C |
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