A new and efficient method for the synthesis of 3,4-disubstituted pyrrolidine-2,5-diones |
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| Authors: | Ilieva Eleonora D Petkova Nevena I Nikolova Rositca D |
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| Affiliation: | Sofia University St. Kliment Ohridski, Faculty of Chemistry and Pharmacy, 1, J. Bourchier Blvd., Sofia 1126, Bulgaria. |
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| Abstract: | A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined. |
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