Synthesis and intramolecular cyclisation of ortho-hydroxy-2,3,3,3-tetrafluoropropiophenone. Formation of 3-fluoro-4-hydroxycoumarin |
| |
Authors: | Wojciech Dmowski |
| |
Institution: | Institute of Organic Chemistry, Polish Academy of Sciences, 00-961 Warsaw Poland |
| |
Abstract: | Acidic hydrolysis of 1-(o-methoxyphenyl)pentafluoropropene gave o-hydroxy-2,3,3,3-tetrafluoropropiophenone and o-methoxy-2,3,3,3-tetrafluoropropiophenone . Compound when treated with aqueous potassium hydroxide or methanolic sodium methoxide gave 3-fluoro-4-hydroxycoumarin . Structure of has been established by spectral means and some chemical reactions. The cyclisation mechanism of is discussed. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|