Polyfluoro-1,2-epoxy-alkanes and -cycloalkanes. Part I. Preparation of some polyfluoro-1,2-epoxycyclohexanes |
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Authors: | Paul L Coe Andrew W Mott John Colin Tatlow |
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Institution: | Chemistry Department, The University of Birmingham, P.O. Box 363, Birmingham B15 2TT Great Britain. |
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Abstract: | Polyfluorocyclohexenes with hydrogen, bromine, and methoxy substituents yielded the corresponding 1,2-epoxides when treated with aqueous sodium hypochlorite containing some acetonitrile. 4,5-Dibromooctafluoro-1,2-epoxycyclohexane was debrominated with zinc dust to give a mixture of octafluoro- and 4H-heptafluoro-1,2-epoxycyolohex- 4-ene. Decafluoro- and 4,5-dibromo-octafluoro-1,2-epoxycyolohexane gave with potassium fluoride in acetonitrile the corresponding potassium perhalogenocyclohexyloxides; heating these gave the analogous cyclohexanones, and treatment with methyl iodide the methyl ethers. The unsaturated 1,2-epoxides also gave methyl ethers on treatment with KF, followed by methylation. |
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