Lateral flow (immuno)assay: its strengths,weaknesses, opportunities and threats. A literature survey |
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Authors: | Geertruida A Posthuma-Trumpie Jakob Korf Aart van Amerongen |
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Institution: | (1) Department of Psychiatry, University Medical Centre Groningen (UMCG), University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands;(2) Agrotechnology and Food Sciences Group, Wageningen University and Research Centre, Bornsesteeg 59, P.O. Box 17, 6700 AA Wageningen, The Netherlands |
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Abstract: | Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring
in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites
in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats,
applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis
with lateral flow (immuno)assays using a literature survey and a SWOT analysis (acronym for “strengths, weaknesses, opportunities,
threats”). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers.
Search terms included “immunochromatography”, “sol particle immunoassay”, “lateral flow immunoassay” and “dipstick assay”. |
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Keywords: | Biomonitoring Clinical chemistry Food safety Forensics Lateral flow assay Phytopathology Veterinary |
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