Pregnane derivatives from Potentilla evestita |
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| Authors: | Khan Rehan Siddiq Farah Fatima Itrat Yasmeen Shazia Karim Aman Malik Abdul Afza Nighat Hameed Saira |
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| Institution: | International Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi - 75270, Pakistan. |
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| Abstract: | A new pregnane derivative, 2,6beta,7beta-trihydroxy-4-methyl-19-norpregna-1,3,5(10)-trien-17-one, has been isolated from the ethyl acetate soluble fraction of Potentilla evestita along with a pregnane derivative, 11alpha,17alpha,21-trihydroxypregna-4,16(22)-diene-3,20-dione, that is reported for the first time as a natural product. Their structures were elucidated with the aid of 1H and 13C NMR spectra and by COSY, HMQC, HMBC and NOESY experiments. |
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