The synthesis of xanthine-8-acetic acid and some of its derivatives |
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Authors: | E. P. Studentsov V. G. Nemets |
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Affiliation: | (1) Lensovet Leningrad Technological Institute, USSR |
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Abstract: | Condensation of 5,6-diaminouracil with ethyl cyanoacetate yields xanthine-8-acetonitrile which is hydrolyzed by alkalis to xanthine-8-acetic acid. Also synthesized were its ethyl ester, acid chloride, and bis(2-hydroxyethyl)amide. |
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