Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex |
| |
| Authors: | Niesel Johanna Pinto Antonio Peindy N'Dongo Harmel W Merz Klaus Ott Ingo Gust Ronald Schatzschneider Ulrich |
| |
| Affiliation: | Lehrstuhl für Anorganische Chemie I-Bioanorganische Chemie, Ruhr-Universit?t Bochum NC 3/74, Universit?tsstrasse 150, D-44801 Bochum, Germany. |
| |
| Abstract: | Cell viability studies of HT29 colon cancer cells treated with the CO-releasing compound [Mn(CO)(3)(tpm)]PF(6) revealed a significant photoinduced cytotoxicity comparable to that of established agent 5-fluorouracil (5-FU), while controls kept in the dark were unaffected at up to 100 microM. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
