Solubility of ibuprofen in supercritical carbon dioxide |
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| Authors: | I. V. Kuznetsova I. I. Gilmutdinov I. M. Gilmutdinov A. A. Mukhamadiev A. N. Sabirzyanov |
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| Affiliation: | 1. Kazan National Research Technological University, Kazan Tatarstan, Russia
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| Abstract: | An experimental apparatus that allows measurement of solubility of solid compounds and liquids in supercritical (SC) fluids in a wide range of temperatures and pressures using a dynamic method is constructed. Experimental data on the solubility of anthracene at 318.1 and 328.1 K and results of the solubility of ibuprofen at 313, 323, and 333 K at 10–30 MPa are obtained. The solubility of ibuprofen in SC CO2 is described using the Peng-Robinson equation of state. Parameters of binary interactions are obtained for the ibuprofen-supercritical CO2 system. |
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