The effect of perfusion on the temperature distribution during thermotherapy: Study on perfused porcine kidneys |
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Authors: | K A Il’yasov B Eissner J Hennig |
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Institution: | 1.Department of Diagnostic Radiology, Section of Medical Physics,Freiburg University Hospital,Freiburg,Germany;2.Department of Experimental Surgery,Freiburg University Hospital,Freiburg,Germany |
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Abstract: | The effect of perfusion on the temperature distribution during radio-frequency hyperthermia and laser-induced thermotherapy
was investigated with the perfused porcine kidney model. The phase shift-based proton resonance frequency shift method was
used to map the temperature distribution. In experiments with modulated perfusion rates it was demonstrated that perfusion
dissipates a significant amount of the absorbed energy and, therefore, the resulting heat distribution is strongly dependent
on the perfusion rate. The measured time course of the temperature distribution was used to estimate the thermal conductivity,
local perfusivity and heat absorption rate of the tissue. These parameters were in a good agreement with literature data.
This approach can also be extended to measure heat absorption and heat transfer parameters in vivo, which can significantly
improve the accuracy of thermotherapy session planning. |
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