首页 | 本学科首页   官方微博 | 高级检索  
     检索      


A novel BDNF gene promoter directs expression to skeletal muscle
Authors:Email author" target="_blank">Gerhard?HeinrichEmail author
Institution:(1) Medical Service, VA Northern California Health Care System, 150 Muir Road, Martinez, CA 94553, USA;(2) Department of Internal Medicine, School of Medicine, University of California at Davis, 4150 V Street, #3100, Sacramento, CA, 95817
Abstract:

Background  

Cell-specific expression of the gene that encodes brain-derived neurotrophic factor (BDNF) is required for the normal development of peripheral sensory neurons and efficient synaptic transmission in the mature central and peripheral nervous system. The control of BDNF gene expression involves multiple tissue and cell-specific promoters that are differentially regulated. The molecular mechanisms that are responsible for tissue and cell-specific expression of these promoters are still incompletely understood.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号