A simple and efficient synthesis of new fluorophore 4-hydroxy pyrazolo[1,5-a]pyridines through a tandem reaction |
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Authors: | Peiling Yan Guiyun Duan Ruixue Ji Yanqing Ge |
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Institution: | 1. College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, Shandong 266071, PR China;2. School of Chemistry and Pharmaceutical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China |
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Abstract: | The cascade reaction of ethyl pyrazole-5-carboxylate with α, β-unsaturated ester leading to 4-hydroxy pyrazolo1,5-a]pyridine derivatives has been developed. A possible mechanism is proposed. The resulting pyrazolo1,5-a]pyridines present strong fluorescence in solutions. |
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Keywords: | Cascade Pyrazolo[1 5-a]pyridine Pyrazole Fluorescence |
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