A simple and fast-response fluorescent probe for hypochlorite in living cells |
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| Authors: | Ruixue Ji Kun Qin Aikun Liu Yan Zhu Yanqing Ge |
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| Affiliation: | School of Chemistry and Pharmaceutical Engineering, Taishan Medical University, Taian, Shandong 271016, PR China |
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| Abstract: | A novel fluorophore pyrido[1,2-a]benzimidazole was synthesized and used as a fluorescent probe for hypochlorite based on the oxidation of hydrazine to carboxyl group. The detection limit was measured to be as low as 7.0?nM. The probe can realize fast-detection for hypochlorite within 60?s. Furthermore, it could be used for imaging in living cells. |
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| Keywords: | Hydrazone Bioimaging Fluorescent probe Hypochlorite |
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