Pd-catalyzed selective decarboxylation/C–H activation coupling of aryl acid with thiazole and oxazole directed by 1,2,3-triazole |
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| Authors: | Xinyuan Ma Yaowen Liu Kai Xie Yubo Jiang |
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| Institution: | Faculty of Science, Kunming University of Science and Technology, Kunming 650500, China |
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| Abstract: | An efficient palladium-catalyzed selective decarboxylation/C–H activation coupling of aryl acid with thiazole and oxazole under the assistance of 1,2,3-triazole ring were developed. This work provides an effective access to build functionalized 1,2,3-triazoles bearing thiazole and oxazole moieties. This method has good substrate compatibility to compose a series of selective heterocyclic compounds in moderate to good yields. |
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| Keywords: | Decarboxylation C–H activation Thiazole Oxazole 1 2 3-Triazole directing group Pd-catalyzed |
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