Strategic innovations for the synthesis of vinigrol |
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Authors: | Vipul V. Betkekar Krishna P. Kaliappan |
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Affiliation: | Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India |
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Abstract: | Since the isolation of unique tricyclic diterpenoid vinigrol, its promising biological activities and complex framework have resulted in numerous synthetic efforts to the total synthesis of this venerable molecule for the past two and half decades. This mini review highlights the significance of various synthetic strategies towards this structurally unique and challenging natural product. |
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Keywords: | Vinigrol Oxy-Cope rearrangement Intramolecular Diels-Alder reaction Domino reactions |
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