Abstract: | Kiamycins B (1) and C (2), two unusual angucyclinones bearing a novel 6,12-epoxybenza]anthracene ring system, were isolated from the cultures of a marine sediment-derived Streptomyces sp. along with one structurally related derivative 3. Their structures and stereochemistries were determined by spectroscopic analyses, single-crystal X-ray diffraction and electronic circular dichroism (ECD) calculations. |