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Kiamycins B and C,unusual bridged angucyclinones from a marine sediment-derived Streptomyces sp.
Authors:Lin Guo  Ze-ping Xie  Qin Yang  Ling-ling Feng  Lu Zhang  Yue-zhi Zhang  Xiao-nian Li  Gennaro Pescitelli  Shu-min Zhang
Abstract:Kiamycins B (1) and C (2), two unusual angucyclinones bearing a novel 6,12-epoxybenza]anthracene ring system, were isolated from the cultures of a marine sediment-derived Streptomyces sp. along with one structurally related derivative 3. Their structures and stereochemistries were determined by spectroscopic analyses, single-crystal X-ray diffraction and electronic circular dichroism (ECD) calculations.
Keywords:Marine actinomycetes  Angucyclinones  Kiamycins  Structural elucidation
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