|
|||||
|
|
Synthesis of unsaturated silyl nitronates via the silylation of conjugated nitroalkenes |
|
| Authors: | Elizaveta A. Khotyantseva Andrey A. Tabolin Roman A. Novikov Yulia V. Nelyubina Sema L. Ioffe |
| Affiliation: | 1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prosp. 47, Moscow 119991, Russia;2. Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia;3. V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Str. 32, Moscow 119991, Russia;4. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov Str. 28, Moscow 119991, Russia |
| Abstract: | A new method for the synthesis of conjugated silyl nitronates from nitroalkenes is described. The procedure has wide substrate scope and is compatible with in situ generation of the substrates from 2-nitroalcohols or 2-chloro-nitroalkanes. A cascade transformation to give 3,4,5,6-tetrahydropyridine N-oxide derivatives was disclosed. |
| Keywords: | Silyl nitronates Nitro compounds One pot reactions [5+2]-Cycloaddition Michael addition |
| 本文献已被 ScienceDirect 等数据库收录！ | |